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From131US$ /night
Check-in
03Mar2026Select date
Check-out
04Mar2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

Via Lardaria 10, Rome, Italy, 00168
-
Close to the Vatican
Great
8.4
8.0
/10
3.6
3.4
/5

Location

Hotel Sisto V is located just 300 meters from the Gemelli Hospital, facilitating accessibility for visiting patients and families. The hotel provides convenient access to several key attractions, being a few minutes from the Vatican and the historic center of Rome. Guests can reach famous sites such as the Colosseum, Trevi Fountain, and Piazza Navona with ease, thanks to the nearby 'Gemelli' urban train stop.

Rooms

The recently renovated rooms at Hotel Sisto V are designed to offer comfort and relaxation for all guests. Each room includes modern amenities, with free WiFi and satellite TV available for entertainment. This variety of accommodations caters to both leisure and business travelers, providing a restful space after a day of exploration.

Dining

Guests can start their day with a rich buffet breakfast offered at Hotel Sisto V. The courteous and qualified staff ensures a pleasant dining experience, serving a range of options to satisfy diverse tastes. The outdoor area provides a comfortable setting for guests to unwind while enjoying meals or refreshments.

Business Facilities

The hotel features a comfortable equipped meeting room suitable for business events and gatherings. This space is designed to accommodate various types of meetings while ensuring necessary amenities are readily available. With professional staff support, the hotel assists in hosting productive business activities.

Outdoor Area

Hotel Sisto V offers a pleasant outdoor area where guests can relax during their stay. This area is designed to provide peace and comfort, allowing visitors to enjoy the beautiful weather of Rome. It serves as an excellent spot for a refreshing break from city explorations.

Highlights

Location: 300 meters from the Gemelli Hospital

Rooms: recently renovated rooms

Dining: rich buffet breakfast

Business: equipped meeting room

“This 3-star hotel is well-placed for visits to Gemelli Hospital and the Vatican, and I think the multilingual staff and transport links make it a practical base. Its varied breakfast gets particular praise; however, some rooms could benefit from an air conditioning upgrade and redesigned bathrooms. Overall, it presents a solid option for business or medical trips.”
Hotel logo
James DavidEditor-in-Chief at Tohotel
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Select your room type

Hotel Sisto V offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
Economy Double Room
2 persons
120 sq. feet 
1 Double bed
Shower
Heating
Superior Double Room Balcony
2 persons
155 sq. feet 
1 King-size bed
Shower
Heating
Triple Room
2 persons
155 sq. feet 
1 King-size bed
Shower
Heating
Single Room no Bidet
2 persons
120 sq. feet 
1 Single bed
Shower
Heating
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Facilities

Hotel Sisto V offers amenities for your comfortable stay and unforgettable experiences
Facilities: Great
8.3/10Review score

General

  • No smoking on site
  • Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Allergy-free rooms
  • Lift
  • Currency exchange
  • Vending machines
  • Smoke detectors
  • Fire extinguishers

Services

  • Paid airport shuttle
  • Valet parking
  • Room service
  • Car hire
  • Laundry
  • Dry cleaning
  • Tours/Ticket assistance
  • Welcome drink

Dining

  • In-room breakfast
  • Snack bar
  • Packed lunches

Business

  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots
  • Babysitting/Child services
  • Children's menu

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Garden area
  • Leisure/ TV room

Room features

  • Air conditioning
  • Heating
  • Mini-bar
  • Soundproofed rooms
  • Dressing area
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Parquet floor
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Hotel Sisto V Location

Via Lardaria 10, Rome, Italy, 00168
Map view
Via Lardaria 10, Rome, Italy, 00168
Nearby
Catholic University of the Sacred Heart
1400 ft
Pope John Paul II
1700 ft
Restaurants
Pizzeria Sacchetti
1000 ft
Via Pineta Sacchetti 450
Burger King
1200 ft
Via della Pineta Sacchetti 251
Bar CentoDolci
1500 ft
Via Bernardo Barbiellini Amidei 2
L' Altro Caffe Roma
1300 ft
Via Tommaso Zigliara 33/35/37 vicino ospedale Gemelli
Piso 35 PUB & Beer Bakery
1700 ft
Via Vittorio Montiglio 35
Cafe Marusa
1900 ft
Via Mosca 27
Pane & Cioccolato
2300 ft
Via Pietro Maffi 105
No Pizza No Party
2600 ft
Via Stefano Borgia 212
Mr Chicken
2500 ft
Via Pietro Maffi 92
Cucineria Centonovanta Trattoria
2900 ft
Via di Torrevecchia 190B
Caffetteria Gelateria Black'n White
3000 ft
Largo Millesimo 15
Explore Rome
Explore Local Delights
Top Attractions
Activities
Dining
Entertainment
Vatican Museums
Vatican Museums
35 minutes' walk
World-renowned for its art collection, including masterpieces by Michelangelo, it offers guided tours and themed visit options.
St. Peter's Basilica
St. Peter's Basilica
40 minutes' walk
An architectural marvel and significant pilgrimage site featuring the iconic dome designed by Michelangelo. Guided tours available.
Castel Sant'Angelo
Castel Sant'Angelo
45 minutes' walk
Historical fortress with stunning views of the city, housing a museum showcasing centuries of Roman history. Special exhibits often featured.
Stadio Olimpico
Stadio Olimpico
30 minutes' walk
Home to major sporting events and concerts, a lively venue for both sports fans and music lovers. Check the calendar for upcoming events.
Parco Santa Maria della Pieta
20 minutes' walk
A serene park ideal for picnics and strolls, featuring lush greenery and relaxing trails, perfect for unwinding after a busy day.
Riserva Naturale di Monte Mario
30 minutes' walk
A scenic natural reserve offering hiking trails with breathtaking views of Rome. Great for nature enthusiasts and photographers.
Guided Cycling Tours
10 minutes' drive
Adventurous tours showcasing Rome's highlights on two wheels. Rentals available; guided options are best suited for adrenaline seekers.
Yoga Classes at Happy Family Park
20 minutes' walk
Relaxing yoga sessions amidst nature, fostering tranquility and health. Classes available for all levels in a peaceful setting.
Pizzeria Sacchetti
Pizzeria Sacchetti
4 minutes' walk
Casual atmosphere renowned for its wood-fired pizzas, made with fresh ingredients. Vegetarian options available; reservations suggested.
L' Altro Caffe Roma
L' Altro Caffe Roma
5 minutes' walk
Charming café serving delicious Italian coffee and pastries in a cozy setting. Ideal for a quick breakfast or afternoon treat.
Piso 35 PUB & Beer Bakery
Piso 35 PUB & Beer Bakery
6 minutes' walk
A unique pub experience blending craft beers and freshly baked goods. Relaxed vibe with an extensive drink menu; all dietary needs accommodated.
Burger King
Burger King
5 minutes' walk
Familiar fast food option for quick bites, ideal for families. Known for its burgers and fries; convenient for a no-fuss meal.
Teatro Olimpico
10 minutes' drive
Featuring a variety of live performances from theater to concerts, this venue has something for everyone. Check schedules for family-friendly shows.
Testaccio Market
15 minutes' drive
Vibrant market known for local food stalls and arts, ideal for visitors looking to experience Rome's culinary scene. Open most days.
Jazz in Roma
15 minutes' drive
Charming venue hosting weekly jazz nights and live music. Perfect for couples and solo travelers seeking a relaxed night out.
Cinemas in Cinecittà
20 minutes' drive
Cinecittà showcases both blockbusters and indie films, ideal for movie lovers. Offers special screenings and family-friendly films regularly.
Getting around
City Centre
Rome6 min  ·  2.5 mi
Airports
Roma-Fiumicino Airport (FCO)45 min  ·  18.3 mi
Rome Ciampino Airport (CIA)53 min  ·  21.9 mi
Train
Roma San Pietro Train Station7 min  ·  2.6 mi
Underground
Battistini Metro30 min  ·  1.6 mi
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Property information and rules
Check-in
from 14:00-23:30
Check-out
until 11 am
Guest Parking
Private parking is possible on site (reservation might be needed) at EUR 10 per day.
Internet
Wireless internet is available in the entire hotel for free.
Breakfast
The hotel offers a full breakfast at the price of EUR 7 per person per day. 
Children & extra beds
Maximum capacity of extra beds in a room is 1. 
Pets
Pets are allowed on request.
Languages
English, German, Spanish, Italian, Russian, Ukrainian
Year renovated:
2010
Number of floors:
4
Number of rooms:
46

Reviews and Ratings

Feedback about Hotel Sisto V from previous guests about their experience.
Review score
Based on 323 verified reviews
8.4/10
Great
90%
Recommend
Breakfast
7.4/10
Cleanliness
8.7/10
Comfort
8.5/10
Facilities
8.3/10
Free Wi-Fi
7.8/10
Location
8.6/10
Paid Wi-Fi
7.8/10
Staff
9.0/10
Value for money
8.2/10
Pros
Great staff
Clean rooms
Delicious breakfast
Quiet neighborhood
Comfortable beds
Cons
Ambulance sounds
Further location
Cold temperature
Night transport
Guest reviews
based on 408 reviews
3.5/5
based on 1317 reviews
8.4/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
Open reviews
Questions of the users
About Hotel Sisto V
Is the hotel equipped for guests who use wheelchairs? Are there elevators available for easy access?
12 January 2025
The hotel is fully wheelchair accessible, and elevators are available for convenient access to all floors.
Can late check-in be accommodated for flights arriving in the early hours of the morning?
5 March 2025
The reception operates 24 hours a day, allowing for a hassle-free check-in anytime during the night.
Does the property include a suitable entrance for wheelchair users, considering the presence of stairs in the images?
21 April 2025
The property has an adapted entrance designed for wheelchair users, ensuring easy access.
Is there a charge for shuttle services to and from the airport?
9 February 2025
Airport transfer services are available at an additional fee.
What is the fixed rate for taxi services from the airport to the hotel?
30 March 2025
The fixed rate for taxi service from the airport to the hotel is €70.00 each way.
What are the official check-in and check-out hours? Is there flexibility for late-night arrivals?
17 April 2025
Check-in and check-out hours are flexible, with round-the-clock availability for guests arriving late at night.
Are there options for airport transfers, and how is the cost determined?
14 February 2025
Airport transfers can be arranged based on the airport location and the number of guests, with costs varying accordingly.
How far is the hotel from popular attractions like the Vatican and the Colosseum?
3 March 2025
The hotel is situated approximately 4 kilometers from the Vatican and around 6 kilometers from the Colosseum, making it an ideal location for sightseeing.
Is there a breakfast included, and what does it typically consist of?
29 January 2025
A rich breakfast buffet is provided, offering a variety of options to start the day.
Does the hotel provide a relaxing outdoor area for guests to enjoy?
28 February 2025
Yes, there is a pleasant outdoor area available for guests to unwind, especially nice during the warmer months.

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