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Check-in
18Jan2026Select date
Check-out
19Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

167 West Main Street, Lexington, Kentucky, United States, 40507
-
Steps from Rupp Arena
Great
8.2
8.7
/10
4.5
4.2
/5

Rooms: Art and Comfort

21c Museum Hotel Lexington features rooms with original artwork, free Wi-Fi, and Malin + Goetz bath items. Room options include the City Queen with a queen bed, the Deluxe King, and the Deluxe Double Queen with two queen beds and city views. Corner King rooms have large windows with blackout drapes. Suites range from the Skylight Suite with a skylight and separate living area, to the Deluxe Suite with a dining/work area. The 21c Suite, the largest, features downtown views, a king bed, dressing area, powder room, and dining/work area. Two-bedroom suites are available with two bathrooms, a living space, and options for two to four beds. Nightwatch is a hotel room and site-specific installation by artist Chris Doyle.

Dining: Lockbox Restaurant

Lockbox features a bar and lounge for drinks and casual dining. The culinary team prepares catering menus. Local providers and Kentucky's limestone-rich soil influence the frequently changing menus. Guests can find drinks at Ona, a cozy bar a few blocks away. The hotel offers a limited edition bottle of 21c Select bourbon and wine options from Wine + Market.

Leisure and Activities

21c Museum Hotel Lexington has over 7,000 square feet of exhibition space. The hotel displays site-specific installations, like Tomorrow's Weather by Bigert & Bergstrom. The Main Gallery transforms into a dance club with a DJ. Guests can explore Lexington's art scene, including Pieke Bergmans' Totally in Love and SOFTlab's Spectralline. Nearby attractions include horse farms and bourbon distilleries. Guests can also visit the Ice Rink in Triangle Park, Natural Bridge State Resort Park, and Daniel Boone National Forest. The hotel provides curated experiences, like microbrewery tours and horse farm visits.

Location: Downtown Lexington

21c Museum Hotel Lexington is 15 km from Blue Grass Airport. The hotel is near Triangle Park, the University of Kentucky Art Museum, the Mary Todd Lincoln House, and Thoroughbred Park. It is located in the historic Fayette National Bank Building, originally designed by McKim, Mead and White. The hotel is near local breweries, distilleries, and horse farms.

Services and Amenities

21c Museum Hotel Lexington offers a business center and laundry service. The hotel is pet-friendly. Event spaces include a Main Gallery for up to 250 guests and five private galleries for 10 to 100 guests. There is one conference room for up to 12 people with audio visual capabilities. The hotel provides valet parking for $30 per night. The hotel has a sustainability fee of $5.00 to support green initiatives. Cribs are available upon request at no additional charge. Rollaway beds are available for a nightly fee of $30.

“21c Lexington distinguishes itself with a keen blend of contemporary art and sustainable luxury. Its downtown location and Lockbox restaurant, emphasizing seasonal menus, provide a unique draw for discerning guests. I appreciate the hotel's dedication to eco-conscious practices and local partnerships.”
Hotel logo
James DavidEditor-in-Chief at Tohotel
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Select your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
City Queen Room
2 persons
240 sq. feet 
1 King-size bed
Shower
Coffee machine
Deluxe Queen Room
2 persons
360 sq. feet 
2 King Size Beds
Shower
Coffee machine
Deluxe King Room
2 persons
335 sq. feet 
1 King-size bed
Shower
Coffee machine
Corner King Room
2 persons
435 sq. feet 
1 King-size bed
Shower
Coffee machine
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Price and Room Availability Calendar

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Facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences

General

  • No smoking on site
  • Free Wi-Fi
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • 24-hour security
  • Luggage storage
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre
  • Yoga class

Services

  • Paid shuttle service
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Tours/Ticket assistance
  • Welcome drink

Dining

  • In-room breakfast
  • Restaurant
  • Snack bar
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Children's menu

Room features

  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Dressing area
  • Tea and coffee facilities
  • Dining table
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock
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Dining Onsite

21C Museum Hotel Lexington presents a delightful array of dining options that celebrate local flavors and culinary creativity. From the innovative takes on American cuisine at Lockbox to the charming atmosphere of nearby cafes, guests are invited to indulge in bold tastes and authentic experiences.
21C Museum Hotel Lexington Restaurant photo

Lockbox

American, Local
Ambiance
A chic and contemporary space that exudes warmth, perfect for casual gatherings or intimate dinners.
Key Offerings
Highlights include a diverse menu accommodating vegetarian, vegan, gluten-free, and dairy-free preferences, with breakfast and dinner options that showcase local ingredients.
Reservation
Recommended
Wednesday 7:00 AM - 11:00 AM, 5:00 PM - 10:00 PM; Thursday 7:00 AM - 11:00 AM, 5:00 PM - 10:00 PM; Friday 7:00 AM - 11:00 AM, 5:00 PM - 10:00 PM; Saturday 7:00 AM - 11:00 AM, 5:00 PM - 11:00 PM; Sunday 10:00 AM - 2:00 PM, 5:00 PM - 9:00 PM.

Red River Rockhouse

Café, Local
Ambiance
A cozy family-owned café that emphasizes sustainability and a welcoming vibe, ideal for casual meals.
Key Offerings
Focus on locally sourced ingredients, offering a menu that delights both the palate and the conscience.
Reservation
Not needed
Hours vary.

La Cabana Mexican Restaurant

Mexican
Ambiance
A vibrant atmosphere perfect for unwinding with family and friends over flavorful meals.
Key Offerings
Indulge in delightful burritos and robust margaritas, bringing a taste of Mexico to Lexington.
Reservation
Not needed
Hours vary.

Miguel's Pizza

Italian, Casual
Ambiance
A laid-back eatery known for its spirited vibe, appealing to both pizza lovers and adventurers.
Key Offerings
Famous for sliced pizzas, the restaurant adds a fun twist with creative toppings in a relaxed setting.
Reservation
Not needed
Hours vary.

Location

167 West Main Street, Lexington, Kentucky, United States, 40507
Map view
167 West Main Street, Lexington, Kentucky, United States, 40507
Nearby
430 West Vine Street
Rupp Arena
1600 ft
Museum
Hunt-Morgan House
1600 ft
Event hall
Lexington Convention Center
1500 ft
Theatre
Kentucky Theatre
1200 ft
440 W Short St
Explorium
1500 ft
University
University of Kentucky
300 ft
Park
Triangle Park
1200 ft
Church
St Paul the Apostle Catholic Church
1500 ft
Library
Lexington Public Library Ceiling Clock and Foucault Pendulum
900 ft
Shopping Area
Victorian Square Shoppes
1200 ft
Square
Phoenix Park
600 ft
Gallery
Limestone Blue
500 ft
Lexington Financial Center
Isaac Murphy Memorial Art Garden
500 ft
Gallery
Pam Miller Downtown Arts Center
800 ft
Gallery
ArtsPlace
800 ft
7285 Huron Street
Huron Street Gallery
900 ft
Gratz Park
1700 ft
Restaurants
Bourbon on Rye
300 ft
115 W Main St
Corto Lima
600 ft
101 West Short Street Corner of West Short and North Limestone Streets
School Sushi
400 ft
163 West Short Street
Bluegrass Tavern
500 ft
115 Cheapside
Horse And Jockey
700 ft
131 Cheapside
Buddha Lounge
700 ft
109 N Mill St
Explore Lexington
Local Experiences Near 21C Museum Hotel Lexington
Top Attractions
Activities
Dining
Entertainment
Mary Todd Lincoln House
Mary Todd Lincoln House
9 minutes' walk
Historic home of Mary Todd Lincoln, featuring guided tours and rich Civil War history.
Thoroughbred Park
Thoroughbred Park
12 minutes' walk
A sculptural park celebrating Kentucky's horse racing culture, perfect for a leisurely stroll.
University of Kentucky Art Museum
University of Kentucky Art Museum
13 minutes' walk
Art museum showcasing American and European art, with free admission days available.
Rupp Arena
Rupp Arena
6 minutes' walk
Home to local sports teams and major concerts, hosting a variety of live events year-round.
Horseback Riding in Horse Country
12 minutes' walk
Guided horseback riding tours showcasing Kentucky's scenic landscapes and famous estates.
Yoga at the Arboretum
35 minutes' drive
Relaxing yoga classes amidst beautiful gardens. Check for seasonal schedules and booking.
Bourbon on Rye
Bourbon on Rye
1 minute' walk
Casual eatery featuring Southern comfort food and an extensive bourbon selection.
Corto Lima
Corto Lima
3 minutes' walk
Modern Mexican cuisine with a vibrant atmosphere and farm-to-table ingredients.
School Sushi
School Sushi
2 minutes' walk
Unique sushi restaurant known for innovative rolls and a fun, relaxed dining experience.
Kentucky Theatre
Kentucky Theatre
5 minutes' walk
Historic theater featuring independent films and live performances, with a charming vintage vibe.
Manchester Music Hall
Manchester Music Hall
15 minutes' walk
A vibrant venue hosting live music and entertainment events suitable for all ages.
Getting around
City Centre
Lexington5 min  ·  1400 ft
Airports
Blue Grass Airport (LEX)21 min  ·  8.5 mi
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
is available in public areas for free.
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are allowed on request.
Number of floors:
15
Number of rooms:
85
Questions of the users
About 21C Museum Hotel Lexington
Are pets welcome at this hotel, and what are the associated fees?
5 January 2024
Yes, pets are allowed with a one-time fee of $50, and there is no restriction on the number of pets in the room.
What parking options are available for guests, and what are the costs?
12 February 2024
Valet parking is offered at $30 per night, which includes unlimited in and out privileges. Nearby, a public parking garage caps at $12 per day.
What is the early check-in policy for guests who arrive before standard check-in time?
18 March 2024
Guests can check in early without charge as soon as their room is ready. To guarantee an early arrival before 4 PM, a reservation for the previous night may be necessary.
Can two connecting rooms be booked for a larger party?
25 April 2024
Yes, connecting rooms are available across various configurations. Requests for connecting rooms can be noted during booking.
Are there options for spa services at the hotel?
2 May 2024
While there are no onsite spa facilities, arrangements can be made for offsite spa services or in-room massages.
Is complimentary Wi-Fi available for guests during their stay?
14 June 2024
Yes, high-speed Wi-Fi is free for all guests throughout the property.
Are there advance booking discounts for educators?
20 July 2024
Currently, there isn't a specific educator discount. However, various promotions may be available for all travelers.
Is it possible to request extra beds for a guest room?
10 August 2024
Cribs are available at no extra charge, while rollaway beds can be provided for a nightly fee of $30.
What safety measures are in place around the hotel and neighborhood?
15 September 2024
The area is considered very safe, with 24-hour staff presence, overnight security, and a police station located just two blocks away.
What on-site dining options are available for guests?
22 October 2024
The hotel features Lockbox, a unique restaurant that offers a lively dining experience with a focus on local ingredients.

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