Book on our site
Up to 10% cheaper
than Booking.com
Check rooms and rates
From161US$ /night
Check-in
19Jan2026Select date
Check-out
20Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

220 North Main Street, Greenville, South Carolina, United States, 29601
-
Next to Falls Park on the Reedy River
Great
8.6
8.4
/10
4.2
3.9
/5

Rooms at Hyatt

All 327 rooms include laptop-compatible safes and premium bedding. Rooms offer workspaces suitable for laptops and air conditioning. Guests will find comforts such as a separate furnished seating area and dining area. Room features include ironing facilities, heating, air conditioning, plus tea and coffee facilities. Bathrooms provide free toiletries, a bathtub, and a sink. A flat-screen TV with cable channels and a coffee maker are standard. Some rooms feature skyline views, views of the hotel's atrium, or panoramic views of the Blue Ridge Mountains. Some quadruple rooms are wheelchair accessible with a toilet with grab rails.

Dining at Roost

Roost is a farm-to-table restaurant with handcrafted food and drinks and American cuisine. The restaurant features brunch and happy hour. Guests can get a drink at one of the 2 bars/lounges. Nearby dining includes Blue Ridge Brewing Co. Tree-lined streets lead to over 100 restaurants and shops in downtown Greenville, where guests can walk to over 60 restaurants and shops.

Leisure and Activities

Guests can enjoy an outdoor pool, a restaurant, and a lounge. The fitness center features Life Fitness treadmills, ellipticals, cross-trainers, and exercise bikes. Guests can complete their workout with a selection of free weights, circuit weights, ropes, and mats. Jogging paths are onsite. Guests can check out an event or game at Bon Secours Wellness Arena or catch a concert. The hotel is 2 km from Falls Park on Reedy River. The Children's Museum of the Upstate and Greenville Zoo are nearby.

Location and Proximity

Hyatt Regency-Greenville is in the heart of Greenville, downtown on NOMA Square, and 400 metres from Greenville County Museum of Art. It is in Downtown Greenville with art galleries, shops, award-winning restaurants, and Falls Park on the Reedy River. Landmarks nearby include Cleveland Park (2.5 km), Beattie House (1 km), and Falls Park on the Reedy (1 km). Greenville Downtown Airport is within 2 km. Other landmarks are Noma Square (0.3 km), Dark Corner Distillery (0.5 km), Upcountry History Museum (0.5 km), and Kilgore Lewis House (0.5 km).

Hotel Services

The hotel offers services and amenities designed to provide comfort and convenience. The 24-hour business center, located in Max's Library on the lobby level, includes computer access, equipment rental, color and laser jet printers, a fax machine, and high-speed internet access. The property has 25000 square feet of space consisting of conference space and meeting rooms. An airport transfer service is offered to-and-from Greenville Downtown Airport. Other amenities include dry cleaning/laundry services and an outdoor entertainment area. Safety features include a fire extinguisher, a smoke detector, a security system, and a first aid kit. Any occupied guestroom is accessed at a minimum of once within a 24-hour period.

“What stands out here is the location, right on North Main Street, putting you within steps of Greenville's shops, restaurants, and nightlife. The farm-to-table dining at Roost Restaurant feels like a real draw. It strikes me as a solid choice, especially for those wanting to explore downtown.”
Hotel logo
James DavidEditor-in-Chief at Tohotel
View all

Select your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
Deluxe King Room
2 persons
360 sq. feet 
1 King-size bed
Bathtub
Air conditioning
King Room Accessible Shower Disability Access
2 persons
345 sq. feet 
1 King-size bed
Shower
Air conditioning
King Room Accessible Tub Disability Access
2 persons
345 sq. feet 
1 King-size bed
Bathtub
Air conditioning
Queen Room Two Queen Beds
2 persons
345 sq. feet 
2 King Size Beds
Coffee machine
Bathtub
Click button to see more rooms
Show all rooms
Show all roomsLess

Price and Room Availability Calendar

Check availability and prices for your dates now!

Facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences

General

  • No smoking on site
  • Wi-Fi
  • On-site car park
  • Handicap parking
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • 24-hour security
  • Luggage storage
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre
  • Hiking
  • Cycling
  • Bowling
  • Golf course

Guest Parking

  • Electric kettle

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Shops/Commercial services
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots
  • Children's menu

Spa & Leisure

  • Seasonal outdoor pool
  • Beach umbrellas
  • Sun loungers
  • Live entertainment
  • Sun terrace
  • Leisure/ TV room
  • Jacuzzi

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Terrace
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Bathtub
  • Free toiletries
  • Sink

Self-catering

  • Electric kettle

Media

  • Flat-screen TV
  • Direct dial telephone
  • CD player
  • AM/FM alarm clock

Room decor

  • Curtains
Show more

Dining Onsite

At Hyatt Regency - Greenville, dining options are both inviting and diverse, showcasing a delightful selection of American cuisine. Guests can enjoy meals in a warm, family-friendly atmosphere, perfect for any occasion, whether it's a casual breakfast or a leisurely dinner.
Hyatt Regency - Greenville Restaurant photo
Hyatt Regency - Greenville Restaurant photo
Hyatt Regency - Greenville Restaurant photo

Roost Restaurant

American cuisine
Ambiance
Family-friendly with modern touches, featuring a separate furnished seating area for comfortable dining.
Key Offerings
Enjoy brunch and happy hour specials, complemented by a relaxed dining experience in a vibrant setting.
Reservation
Reservations not needed.
Open for breakfast from 6:30 AM to 10:00 AM, and lunch and dinner from 11:30 AM to 9:00 PM daily.

Location

220 North Main Street, Greenville, South Carolina, United States, 29601
Map view
220 North Main Street, Greenville, South Carolina, United States, 29601
Nearby
Museum
The Children's Museum of the Upstate
1700 ft
Event hall
Kilgore Lewis House
1800 ft
Church
Christ Episcopal Church
1900 ft
14 S Main St
Dark Corner Distillery
1100 ft
220 N Main St
Noma Square
200 ft
Gallery
The Art Cellar
200 ft
South Main Street Court Square
Joel Roberts Poinsett
1700 ft
650 N Academy St Bon Secours Wellness Arena
Greenville Swamp Rabbits
1900 ft
Gallery
Artists Guild Gallery Of Greenville
100 ft
S Main St
Downtown Greenville
1800 ft
430 N Main St
American Legion
1600 ft
Restaurants
Antonino Bertolo's Pizza and Wine Bar
100 ft
200 N Main St Ste 103
Subway
600 ft
225 N Main St
Jersey Mike's Subs
500 ft
233 N Main St Suite 10
Menkoi Noodle House
800 ft
241 N Main St
Vic's Pizza
600 ft
12 E Coffee St
Sully's Steamers
700 ft
6 East Washington Street
Groucho's Deli
800 ft
20 E Coffee St # SC
Charleston Sports Pub
600 ft
15 W Washington St
Explore Greenville
Local Highlights
Top Attractions
Activities
Dining
Entertainment
Falls Park on the Reedy
Falls Park on the Reedy
14 minutes' walk
A picturesque park featuring trails, waterfalls, and the iconic Liberty Bridge, great for relaxation and photography.
Greenville Zoo
Greenville Zoo
25 minutes' walk
Home to over 300 animals, this family-friendly zoo provides educational programs and a lovely picnic area.
Upcountry History Museum
Upcountry History Museum
10 minutes' walk
An engaging museum showcasing the history of the Upcountry region through interactive exhibits and local artifacts.
Bon Secours Wellness Arena
Bon Secours Wellness Arena
9 minutes' walk
A multipurpose arena hosting concerts, sports events, and family shows, perfect for an exciting night out.
Hiking in Timmons Park
30 minutes' walk
Beautiful trails offer outdoor adventures amidst scenic views, ideal for nature lovers and fitness enthusiasts.
Yoga at Unity Center of Myrtle Beach
10 minutes' drive
Relaxation-focused yoga classes that cater to all levels, promoting mindfulness and wellness.
Biking the Swamp Rabbit Trail
10 minutes' drive
A scenic 22-mile long trail perfect for thrilling bike rides and a great way to explore Greenville's landscapes.
Antonino Bertolo's Pizza and Wine Bar
Antonino Bertolo's Pizza and Wine Bar
1 minute' walk
Italian eatery known for its authentic pizza and extensive wine list in a cozy setting. Reservations recommended.
Menkoi Noodle House
Menkoi Noodle House
3 minutes' walk
Casual spot offering delicious ramen and Japanese dishes in a vibrant atmosphere. Vegetarian options available.
Subway
Subway
3 minutes' walk
Familiar chain for customizable sandwiches and salads. A quick and convenient option for on-the-go meals.
Dark Corner Distillery
Dark Corner Distillery
4 minutes' walk
Local distillery providing tours and tastings of spirits. Experience craft cocktails in a relaxed environment.
The Peace Center
15 minutes' walk
A cultural hub for live performances ranging from theater to concerts. Check for family-friendly events.
Getting around
City Centre
Greenville5 min  ·  1400 ft
Airports
Greenville-Spartanburg International Airport (GSP)34 min  ·  13.8 mi
Asheville Regional Airport (AVL)118 min  ·  48.5 mi
Train
Greenville County Art Museum5 min  ·  1400 ft
Want to see Exclusive Early Booking Rate?
Get exlusive rates right now!
Check Rates
Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
Public parking is possible on site at USD 7 per day.
Internet
is available in for free.
Breakfast
The hotel offers a full breakfast at the price of US$21 per person per day. 
Children & extra beds
There are no cots provided in a room.  There are no extra beds provided in a room. 
Pets
Pets are allowed on request.
Languages
Spanish, Turkish
Year renovated:
2009
Number of floors:
8
Number of rooms:
325

Next best alternative

Consider them for your next trip.
Check-in
19Jan2026Select date
Check-out
20Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Need more options?
Check Top hotels near Hyatt Regency - Greenville
Holiday Inn Express & Suites Greenville-Downtown By Ihg Exterior photo
Mobile-only price

Holiday Inn Express & Suites Greenville-Downtown By Ihg

8.9
Great516 reviews
307m from property
USD 129USD 116
per night
Aloft Greenville Downtown Exterior photo
Mobile-only price

Aloft Greenville Downtown

9.0
Perfect374 reviews
359m from property
USD 179USD 161
per night
The Westin Poinsett, Greenville Exterior photo
Mobile-only price

The Westin Poinsett, Greenville

9.0
Perfect178 reviews
460m from property
USD 161USD 144
per night