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16Oct2025Select date
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Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

700 West Main Street, Louisville, Kentucky, United States, 40202

Rooms & Suites

21c Louisville, located in Downtown Louisville, offers accommodations for families, couples, business, and solo travelers. Each guest room preserves the history of former bourbon and tobacco warehouses. Rooms feature ironing facilities, heating, air conditioning, tea and coffee facilities, a mini-bar, and trouser press. Select rooms include a patio and soundproofed walls. Bathrooms include free toiletries, and rooms have a flat-screen TV and carpeted floor. Quadruple rooms have city views and two beds. Triple rooms offer city views and one bed. Suites have a living room, a separate bedroom, a bathroom with free toiletries, a flat-screen TV, a mini-bar, a tea and coffee maker, and a wardrobe. The largest room features an open floor plan with a king-sized bed, a living and dining area, and a connecting king bedroom. One suite includes a well-fitted kitchen with a refrigerator, kitchenware, and a microwave. Some rooms include premium Bryte Restorative Sleep Bed + Experience, which allows for personalizing the sleep experience from temperature to firmness.

Dining Options

Proof on Main, led by Kentucky native and Executive Chef Cody Stone, offers menus that showcase a unique approach to Southern and Appalachian-inspired cuisine. The Proof on Main lounge includes the 21c Selects Private Barrel Program, and is ranked as one of the best bourbon bars in the country. Proof on Main's culinary team prepares catering menus tailored to specific needs. The hotel has events like the Fork & Bottle dinner series featuring guest distillers and spirits from throughout the region, and the annual Hog & Barrel dinner featuring Pappy Van Winkle.

Leisure & Entertainment

21c Louisville is a multi-venue contemporary art museum with changing exhibits and installations placed around its public spaces. Guests can sleep in a museum. It features more than 9,000 square feet of exhibition space where curated exhibitions and site-specific installations reflect contemporary culture. Works highlight the notion of the glitch, and posit new pathways and possibilities for the future. The museum is within a half mile of the Kentucky Museum of Art & Craft, Frazier International History Museum and Muhammad Ali Center. Local art in every form is displayed at Revelry Boutique Gallery, which showcases over 150 regional artists. Guests can view selected artworks from the 21c exhibition Still, Life, shared by 21c Museum Hotel Louisville manager Karen Gillenwater and art therapist Jennifer Kramer. There are site-specific installations. Events such as Fork & Bottle dinner series featuring guest distillers and spirits from throughout the region. Reflexology focuses on ' reflex points ' in the feet, hands and ears that relate to specific organs and glands in the body. A sports massage helps athletes prepare their bodies for optimal performance, recover after a big event, or function well during training. Guests can select a deep tissue massage to relieve the deeper structures of their muscle and connective tissue. There is also River City Tintype.

Location and Transportation

21c Museum Hotel Louisville is in Downtown Louisville near museums like the Muhammad Ali Center and the Louisville Slugger Museum & Factory. It is within a half mile of the Kentucky Museum of Art & Craft. Guests can access the free electric ZeroBus nearby, two roads down from the hotel, which takes a circulator route along Main and Market streets, visiting sites of the downtown area such as Whiskey Row and Slugger Field. The hotel is near historic Whiskey Row, where you'll find Old Forester, known as ' the first bottled bourbon.' It is near the Kentucky Performing Arts Center. Four large windows provide views of 7th Street, Main Street and the Ohio River. Landmarks nearby include Flame Run Glass Studio and Gallery (0.5 km), the Cathedral of the Assumption (0.5 km), Evan Williams Bourbon Experience (0.3 km), the Kentucky Museum of Art and Craft (0.3 km), Fourth Street Live (1 km), Louisville Slugger Field (1.5 km), The Frazier History Museum (0.3 km), and The Belvedere (0.3 km).

Hotel Services

21c Louisville is an event venue for celebrations, from unions and reunions to milestones and anniversaries, to product launches and corporate kickoffs. Dedicated event staff will help you treat your crew to an unforgettable occasion. There are four private galleries to accommodate meetings or events for groups of 10 to 60. The hotel is happy to get creative in reducing the environmental impact of your meeting or event, and event planners can provide guidance in planning an eco-conscious meeting or event.

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Select your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
Room Balcony
Max:
2 persons
29 m² 
Bed options:
1 King-size bed
Shower
Coffee machine
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Deluxe King Room
Max:
2 persons
31 m² 
Bed options:
1 King-size bed
Shower
Coffee machine
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Corner Suite
Max:
2 persons
61 m² 
Bed options:
1 King-size bed
Shower
Coffee machine
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Getting around

A list of all available modes of transport

City Centre
Louisville 1.9 km
Airports
Louisville (SDF) 11.9 km

Facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Locker room
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers

Sports & Fitness

  • Fitness centre
  • Yoga class

Guest Parking

  • Cookware/ Kitchen utensils

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area
  • Outdoor dining area

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots

Spa & Leisure

  • Spa & wellness centre
  • Sauna
  • Turkish bath
  • Steam room
  • Full body massage

Room features

  • Air conditioning
  • Heating
  • Mini-bar
  • Soundproofed rooms
  • Patio
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Self-catering

  • Cookware/ Kitchen utensils

Media

  • Flat-screen TV

Room decor

  • Carpeted floor
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Location

700 West Main Street, Louisville, Kentucky, United States, 40202
Map view
700 West Main Street, Louisville, Kentucky, United States, 40202
Nearby
Museum
Louisville Slugger Museum & Bat Factory
180 m
Museum
Muhammad Ali Center
280 m
Museum
Kentucky Science Center
140 m
Museum
The Frazier History Museum
260 m
Museum
Kentucky Museum of Art and Craft
70 m
528 W Main St
Evan Williams Bourbon Experience
200 m
Gallery
Flame Run Glass Studio and Gallery
300 m
500 W Main St
The Belvedere
250 m
Night club
Jimmy Can't Dance
90 m
801 W Main St
Michter's Fort Nelson Distillery
150 m
Library
Sons of the American Revolution Genealogical Research Library
190 m
120 N 10th St
Kentucky Peerless Distilling Co
480 m
401 W River Rd
Belle of Louisville Riverboats
580 m
Restaurants
Proof On Main
10 m
702 West Main Street
Mussel & Burger Bar Downtown
60 m
113 S 7th St Located in Louisville's Central Business District
Bristol Bar & Grille
110 m
614 W Main St
Atlantic No. 5
160 m
605 W Main St Located in Louisville's Central Business District.
Los Aztecas Mexican Restaurant
180 m
445 E Market St
Vincenzo's Italian Restaurant
430 m
150 S 5th St
Jockey Silks Bourbon Bar
480 m
140 N 4th St 2nd Floor - West Tower
Dish on Market
470 m
434 W Market St
Quiznos
540 m
223 S 5th St
Swizzle Dinner & Drinks
530 m
140 N Fourth St 25th Floor
Cafe Magnolia
590 m
140 N 4th St Galt House Hotel
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Check-in
16Oct2025Select date
Check-out
17Oct2025Select date
Rooms and Guests2 Guests, 1 Room